There’s a Despicable Me 4. There has yet to be a Megamind 2, but we’ve had four Despicable Me’s and 2 Minion films. It just doesn’t seem fair, but the Minions are essentially a money making machine for Dreamworks, so they’ll keep making movies as long as the cash keeps flowing.
In the new film, Gru has everything he could want. He’s got a wife, his adopted kids, and a new baby of his own. Now an old villain is out for revenge and he has to take them all into hiding to keep them safe.